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Research Journal of Medical Sciences
Year: 2012  |  Volume: 6  |  Issue: 6  |  Page No.: 286 - 289

Effects of Some Alcoholic Beverages on Haematological and Plasma Biochemical Parameters in Male Albino Rats

K.O. Oyedeji, A.F. Bolarinwa and D.O. Owaduge    

Abstract: The aim of this study was to investigate the effects of some alcoholic beverages (Gulder, Guiness, Chelsea, Rose-Daniel and Bacchus) on haematological and plasma biochemical parameters in male albino rats. Treatment of rats for 42 days with all the alcoholic beverages (except Gulder and Rose-Daniel) caused significant (p<0.05) increase in MCH value while treatment of rats with Guiness caused significant (p<0.05) decrease and increase in the neutrophil and lymphocyte values, respectively relative to their controls. Treatment of rats with all the alcoholic beverages caused no significant (p>0.05) changes in platelet, total WBC and RBC counts and some indices relating to it (Hb, PCV, MCV and MCHC) relative to their controls. Treatment of rats with all the alcoholic beverage caused significant (p<0.05) increase in total protein level relative to the control. Treatment of rats with all the alcoholic beverages (except Rose-Daniel) caused significant (p<0.05) increase in the activity of AST relative to the control while treatment of rats with all the alcoholic beverages (except Bacchus and Rose-Daniel) caused significant (p<0.05) increase in the activity of ALT relative to the control.

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