Asian Science Citation Index is committed to provide an authoritative, trusted and significant information by the coverage of the most important and influential journals to meet the needs of the global scientific community.  
ASCI Database
308-Lasani Town,
Sargodha Road,
Faisalabad, Pakistan
Fax: +92-41-8815544
Contact Via Web
Suggest a Journal
Research Journal of Medical Sciences
Year: 2009  |  Volume: 3  |  Issue: 6  |  Page No.: 194 - 197

Effects of Hepatitis B Infection on Haemtological Parameters in Pregnancy in Port Harcourt, Nigeria

M. Eze Evelyn, F.I. Buseri, C.K. Wachukwu and I.N. Nnatuanya    

Abstract: The effect of hepatitis B infection on the haematological parameters of 3,465 apparently healthy pregnant women attending antenatal clinic was studied over a period of 3 years in Port Harcourt, Nigeria. Fifty-seven were HBsAg positive (test) while the remaining 3,408 were HBsAg negative (control) representing a prevalence rate of 1.6%. The mean±SD obtained for Packed Cell Volume (PCV), Haemoglobin concentration (Hb conc.), platelets, total White Blood Cell count (WBC), neutrophils, lymphocytes, eosinophils, basophils and monocytes for hepatitis B positive pregnant women (test) were 22.77±2.86%, 7.26±0.56 g dL-1, 144.23±3.60 x109 L-1, 8.08±0.89x109 L-1, 78.88±2.11%, 16.68±1.87%, 1.49±0.71%, 0.04±0.19% and 2.91±1.27% in the same order. The corresponding values for hepatitis B negative pregnant women (control) were 31.96±2.78%, 10.36±0.76 g L-1, 159.84±20.70x109 L-1, 6.73±1.47x109 L-1, 69.12±3.33%, 24.02±4.01%, 2.96±1.50%, 0.04±0.20% and 3.84±1.60%. The differences between the PCV, Hb conc, platelets, TWBC, lymphocyte, eosinophil and monocyte counts of test were statistically significant from that of the control (p<0.05). There were no significant differences in the neutrophil and basophil counts of the test and control (p>0.05). There was no significant correlation (R<0.50, p>0.01) between the haematological parameters and maternal age, trimester and gravidity in the control subjects. There was however, a strong positive correlation between gravidity and PCV (R = 0.54, p<0.0.01) and haemoglobin concentration (R = 0.61, p<0.01) in the test.

Fulltext    |   Related Articles   |   Back
  Related Articles

Copyright   |   Desclaimer   |    Privacy Policy   |   Browsers   |   Accessibility