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Research Journal of Medicinal Plants
Year: 2017  |  Volume: 11  |  Issue: 3  |  Page No.: 93 - 99

Qualitative Phytochemical Analysis, Antimicrobial Activity and Cytotoxic Effect of Moringa concanensis Nimmo Leaves

Ramaswamy Malathi and Solaimuthu Chandrasekar    

Abstract: Background and Objective: Moringa concanensis Nimmo belongs to the family Moringaceae. This plant is abundantly seen in Perambalur district, Tamilnadu, commonly known as Kattu murungai. Around 20 types of human ailments can be cured by different parts of M. concanensis Nimmo plant. The main objective of this work was phytochemical analysis, antimicrobial activity and cytotoxic activity of M.concanensis leaves. Materials and Methods: The qualitative phytochemical analysis was performed as per the standard procedures previously described. The well diffusion method was used to evaluate the antimicrobial activity of M. concanensis leaves. The MTT assay was used to screen the cytotoxic activity of M. concanensis leaves. The values were expressed as Mean±SD. Significant difference have been observed using one-way Analysis of Variance (ANOVA) by SPSS software version 19.0. The p<0.05, was considered as significant difference. Results: Among all the tested extracts of M.concanensis Nimmo leaves, chloroform, ethyl acetate and aqueous extracts has the lowest number of phytochemicals. The ethanolic extract of the leaves was found rich source of phytochemicals as compared to the other extracts. The Moringa concanensis Nimmo leaves revealed that they have an effective antimicrobial activity. The Staphylococcus aureus possesses maximum inhibition (13.5 mm) in ethanol extract (C3). The Trichophyton rubrum showed 10 mm zone of inhibition in ethanol extract (C3). It possesses the good cytotoxic activity. When the extract concentration was increased, the viability of the cell lines decreased. Conclusion: The findings of this research work were clearly indicates that the leaves of Moringa concanensis Nimmo possess a noteworthy antimicrobial activity and cytotoxic activity. The further research in this plant may leads to develop a novel bioactive compounds.

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