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Research Journal of Medicinal Plants

Year: 2012  |  Volume: 6  |  Issue: 2  |  Page No.: 189 - 196

The Prophylactic Efficacy of Roselle [H. sabdariffa], Moringa [Moringa oleifera], Ginger [Z. officinale] and Ugwu [T. occidentalis] on the Hematology and Serum Protein of Albino Rats [Rattus norvegicus] Exposed to Cement Dust

T. Yahaya, J. Okpuzor and T. Ajayi


The bio-protective efficacy of medicinal plants on cells, organs and systems of animals living in industrial societies were assessed. The prophylactic efficacy of Roselle, Moringa, Ginger, Ugwu and their mixture on the hematology and serum protein of albino rats exposed to cement dust were evaluated. Albino rats, grouped into six comprising ten rats per group, were exposed to cement dust at about 200 m from a cement factory. The control group (group 1) was given distilled water, while the test groups (groups 2-6) were given extracts of Roselle, Moringa, Ginger, Ugwu and the mixture of their extracts, respectively. The rats had access to pellet feeds and water ad libitum and were monitored daily for 180 days. The hematology and blood serum analysis of the test rats showed significant (p<0.05) healthy conditions of the packed cell volume, hemoglobin, red blood cells, white blood cells and serum protein compared to the control rats. Furthermore, the blood of the control rats had time-dependent microcytosis, macrocytosis, anisocytosis, hypochromasia, lymphocytosis and eosinophilia. However, the blood of the test rats showed normal to mild anemic conditions observed in the control rats. The results of the study highlight the efficacy and effectiveness of medicinal plants in disease prevention and control. It also calls for various governments’ participation in medicinal plant research by way of funding.

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