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Research Journal of Medicinal Plants
Year: 2008  |  Volume: 2  |  Issue: 2  |  Page No.: 86 - 91

Antimicrobial Activities of Coula edulis

Bukola C. Adebayo-Tayo and Kola K. Ajibesin    

Abstract: Crude ethanolic extracts of leaves, stem bark, roots and fruits of Coula edulis were analyzed phytochemically and evaluated for their antibacterial and antifungal activities against five clinically isolated pathogenic microorganisms namely: Staphylococcus aureus, Escherichia coli, Salmonella typhi, Pseudomonas aeruginosa and Candida albicans. Flavonoids, saponins, tannins, alkaloids, anthraquinones, terpenes and cardiac glycosides were detected in the ethanolic extracts of the leaves, stem bark, roots and fruits of C. edulis. The highest antimicrobial activity of the ethanolic extract of C. edulis was recorded by stem bark against Ps. aeruginosa and S. aureus. Candida albicans was sensitive only to the leaf and stem bark extracts of C. edulis. The minimum inhibitory concentration of the extracts ranged between 6.25 and 200 μg mL-1. These results suggest that ethanolic extracts of the leaves, stem bark, roots and fruits can be used in the treatment of infectious diseases. The results revealed that the leaves, stem bark, roots and fruits of C. edulis exhibited varying degrees of antimicrobial activity.

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