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Research Journal of Medicinal Plants
Year: 2007  |  Volume: 1  |  Issue: 2  |  Page No.: 60 - 64

Antimicrobial Activity of Cassava Seed Oil on Skin Pathogenic Microorganisms

T.O.S. Popoola, O.D. Yangomodou and A.K. Akintokun    

Abstract: An assessment of the antimicrobial activity of oil extracted from cassava (Manihot esculenta. Crantz) seeds was investigated using agar-well diffusion method against clinical isolates of Staphylococcus aureus, Propionibacterium acnes, Escherichia coli, Pityrosporium ovale and Candida albicans which were isolated from skin infections. The results of the investigation showed that cassava seed oil had inhibitory effect on the growth of all the test isolates. Significant differences (p<0.05) were observed in the degree of inhibition of the isolates, but non-significant variations were observed in inhibition among strains of the same species. The most pronounced inhibition as confirmed by the zones of inhibition around growing colonies was on S. aureus; P. acnes was moderately inhibited, while inhibition of growth of E. coli was mild. Growth inhibition by the oil was not significant (p>0.05) between P. ovale and C. albicans. The inhibitory ability of the oil decreases with a decrease in concentration of oil in the solvent, resulting in marked variation in the minimum inhibitory concentration. The implication of this observation is that the oil may be of medical and particularly dermatological importance

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