Asian Science Citation Index is committed to provide an authoritative, trusted and significant information by the coverage of the most important and influential journals to meet the needs of the global scientific community.  
ASCI Database
308-Lasani Town,
Sargodha Road,
Faisalabad, Pakistan
Fax: +92-41-8815544
Contact Via Web
Suggest a Journal
Research Journal of Environmental Toxicology
Year: 2011  |  Volume: 5  |  Issue: 2  |  Page No.: 152 - 161

Effect of Diazinon on Acetylcholinesterase Activity and Lipid Peroxidation of Poecilia reticulata

Archana A. Sharbidre, Vimal Metkari and Priyanka Patode    

Abstract: The present study was undertaken to evaluate the toxicity and effects of a commercial formulation of the organophosphorous insecticide, Diazinon on acetylcholinesterase and lipid peroxidation activity in the freshwater guppy fish Poecilia reticulata. The fish exposed for 96 h to 50, 100 and 150 μg L-1 concentrations of diazinon at 24.0±1.0°C. Some characteristics of this aquarium water were dissolved oxygen, 7.2-7.9 mg L-1 and conductivity, 0.212-0.260 mS. Each exposure involved 3 treatments with 3 replicates and 1 control (without diazinon). In each aquarium (Volume: 5 L) were 10 fishes. Induction of oxidative stress in various tissues was evidence by increased lipid peroxidation levels. Acetylcholinesterase activity responded positively in a concentration dependent pattern, thus, suggesting the use of these two parameters as potential biomarkers of toxicity associated with contaminations exposure in freshwater fishes.

Cited References   |    Fulltext    |   Related Articles   |   Back
 
 
   
 
 
 
  Related Articles

 
 
 
 
 
 
 
 
 
Copyright   |   Desclaimer   |    Privacy Policy   |   Browsers   |   Accessibility