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Research Journal of Biological Sciences
Year: 2006  |  Volume: 1  |  Issue: 1  |  Page No.: 60 - 62

The Bioactivity of Parinari curatellifolia

T. Oladimeji Audu and O. Joseph Amupitan    

Abstract: The methanol extract of the leaves, stern sand root of parinari curatellifolia Benth, showed moderate cyctotoxicity to brine shrimp with Lc50 values of 1412 µg mL -1, 414 µg mL -1 and 724 µg mL -1 respectively, indicating the presence of bioactive compounds in the extract of this plant. Screening of the stem and root bark extracts for antimicrobial activity against staphylococcus aureus, streptococcus pyogenes, corynebacterium ulceran, Escherichig coli, Salmonella Typhi, candida albicans and Aspergellus niger revealed the extracts to inhibit all pathogens examined except Aspergellus niger. This result implies that these extracts can be used to treat wounds, boils, stomach trouble, diarrhea, food poisoning and fevers. These result further show that the principles of parinari curatellifolia Benth are excellent candidate for additional in vitro pharmacological and efficacy studies.

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