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Pakistan Journal of Nutrition
Year: 2006  |  Volume: 5  |  Issue: 1  |  Page No.: 79 - 82

Lipid Profile of Postmenopausal Women in Calabar, Nigeria

C.A.O. Usoro, C.C. Adikwuru, I.N. Usoro and A.C. Nsonwu    

Abstract: The study aimed to determine the influence of menopause on lipid profile in women. The serum lipid profile consisting of total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), triglyceride (TG), very low-density lipoprotein cholesterol (VLDL-C) and atherogenic index (TC/HDL-C ratio) of 51 postmenopausal women and 43 premenopausal women were estimated colorimetrically using the enzymatic method. The subjects were arranged in two different age ranges of 25 - 45 years and above 45 years of age. The premenopausal and postmenopausal women were recruited and classified using a comprehensive questionnaire. The total cholesterol, LDL-C and atherogenic index of post menopausal women and women above 45 years of age were significantly (p< 0.05) higher and HDL-C lower than those of the premenopausal women and women between 25-45 years of age. No significant differences (p>0.05) were observed in both TG and VLDL-C levels in both the postmenopausal and premenopausal women and also in women in the specified age ranges of 25-45 years and above 45 years. There is therefore evidence of a protective effect of endogenous estrogen against arteriosclerosis and coronary heart disease, as evidenced by increased HDL-C levels and reduced LDL-C and atherogenic index of the premenopausal women.

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