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Pakistan Journal of Biological Sciences
Year: 2010  |  Volume: 13  |  Issue: 15  |  Page No.: 753 - 756

Prevalence and Underlying Etiologies of Neonatal Hypoglycemia

N. Najati and L. Saboktakin    

Abstract: This study aims at determining the prevalence of neonatal hypoglycemia and its underlying causes. In this prospective study 14168 newborns delivered in Tabriz Alzahra Hospital during 2 years were evaluated in regard to blood glucose level at first 24 h of life. Glucose oxidase method with 4-amino-phenazone with a Greiner G-300 was the used method for determining the blood glucose level. Cases with blood glucose <50 mg dL-1 were considered as hypoglycemic newborns. Underlying causes of this condition, as well as the short-term mortality rate were determined. Prevalence of neonatal hypoglycemia was 0.4% (52 newborns). Underlying causes of hypoglycemia were prematurity (61.5%), diabetic mother (13.6%), septicemia (9.6%), perinatal asphyxia (9.6%), stress (3.8%) and neonatal hyperinsulinism (1.9%). The mortality rate was 53.8%, with prematurity as the leading cause of death.

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