Asian Science Citation Index is committed to provide an authoritative, trusted and significant information by the coverage of the most important and influential journals to meet the needs of the global scientific community.  
ASCI Database
308-Lasani Town,
Sargodha Road,
Faisalabad, Pakistan
Fax: +92-41-8815544
Contact Via Web
Suggest a Journal
Pakistan Journal of Biological Sciences
Year: 2008  |  Volume: 11  |  Issue: 9  |  Page No.: 1263 - 1267

Applied Shared Log-Normal Frailty Cox-Proportional Hazard Model to Evaluating the Effect of Vitamin A on the Rat Passive Avoidance Memory

Mohammad Reza Zadkarami    

Abstract: In this research, the Cox-proportional hazard model is used to investigate the effect of various values of vitamin A (3000, 4500 and 6000 IU kg-1) and sesame oil on the passive avoidance memory of rats by shuttle box. Present results confirm that various values of vitamin A do not improve the passive avoidance memory of rats (p<0.05). We found that the animals are clustered (p<0.001) and applying shared log-normal frailty for clustering improves present results (p<0.05) such that sesame oil improves the passive avoidance memory task (p<0.05). Therefore we should consider clustering in the analysis of biological data or we should use cloned animals.

Cited References   |    Fulltext    |   Related Articles   |   Back
   
 
 
 
  Related Articles

 
 
 
 
 
Copyright   |   Desclaimer   |    Privacy Policy   |   Browsers   |   Accessibility