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Pakistan Journal of Biological Sciences
Year: 2000  |  Volume: 3  |  Issue: 11  |  Page No.: 1940 - 1942

Effect of Salinomycin on Immunity of Broiler Chicks

Farzana Rizvi and A. D. Anjum    

Abstract: Broilers (n = 80) were given salinomycin at the rate of 0 ppm (control), 60, 120 and 180 ppm in feed from day-old to eight weeks of age. Broilers showed no clinical signs throughout the study. Non significant effect of various doses of salinomycin was observed on indices of lymphoid organs. Grossly and histologically lymphoid organs of broilers receiving various doses of salinomycin appeared normal. Total leucocyte and lymphocyte count was significantly (p<0.001) decreased in broilers receiving 180 ppm salinornycin. GMT against ND and SRBCs was decreased in broilers receiving higher doses of salinomycin. Wattle response to mallein and wing web response to bovine serum albumin was significantly (p<0.001) decreased in broilers at 120 and 180 ppm salinornycin.

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