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Pakistan Journal of Biological Sciences

Year: 1999  |  Volume: 2  |  Issue: 4  |  Page No.: 1510 - 1513

Effect of Maternal Immunomodulation Alongwith Vaccination on the Production of Colostral Specific Antibodies and Their Transfer to Buffalo Neonates

Z.I. Qureshi, L.A. Lodhi, H. Jamil and A. Sattar


The antibody titre against Pasturella multocida antigen using indirect haemagglutination test from colostrum and serum samples was determined. Twenty four pregnant buffaloes were divided into three equal groups: unvaccinated, vaccinated controls and levamisole hydorchloride treated vaccinated. The colostral and seral antibody titres were significantly higher (P less than 0.05) in levamisole treated vaccinated group of buffaloes. The calves fed on colostrum from these buffaloes also had higher serum antibody titres. It was concluded that levamisole hydrochloride can be use as an immunomodulator alongwith antigen in pregnant animals to elevate colostral antibody titre in dams and lactogenic immunity in their neonates.

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