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Journal of Pharmacology and Toxicology
Year: 2014  |  Volume: 9  |  Issue: 1  |  Page No.: 55 - 61

Anti Diabetic and Anti Dyslipidemia Activities of Cleome gynandra in Alloxan Induced Diabetic Rats

B. Ravichandra, P. Saketh Ram, Ch. Saritha and P. Shankaraiah    

Abstract: The study aim is to investigate the Anti diabetic an anti dyslipidemic activity of Cleome gynandra plant extract in alloxan-induced diabetic rats. The effects of orally administered ethanolic extract of Cleome gynandra on serum glucose and lipid profiles activity were examined in diabetic control and Cleome gynandra treated diabetic rats. While the activity of the blood glucose and lipid profiles, in the serum were assessed. The drugs were administered over a period of 7 days treatment. The Cleome gynandra was significantly (p<0.05) reduced the serum glucose, elevated dyslipidemia levels, SGOT and SGPT levels, in alloxan induced group, Metformin treated group, EECG-I group, EECG-II groups but increased the serum HDL status in all the ethanolic extract Cleome gynandra treated groups, compared with normal control and diabetic control. The present investigation suggested that ethanolic extract of Cleome gynandra was inhibits blood glucose levels and dyslipidemea in diabetes rats.

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