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Journal of Pharmacology and Toxicology
Year: 2008  |  Volume: 3  |  Issue: 4  |  Page No.: 267 - 271

Antimicrobial Spectrum and Phytochemical Study of Walsura trifoliata (A. Juss.) Harms. (Meliaceae) Bark Extracts

K. Sri Rama Murthy and Nagamani Kandimalla    

Abstract: Indigenous uses of Walsura trifoliata (A. Juss.) Harms. (Meliaceae) bark in different parts of Eastern Ghats of Southern Peninsular India, curing skin allergies, astringency and diarrhoeia is wide spread. The objective of the present study was to evaluate the antimicrobial and phytochemical activity of bark extract against pathogenic microorganisms. Successive petroleum ether, methanol, benzene and aqueous extracts of Walsura trifoliata bark were tested for their phytochemical constituents, antibacterial and antifungal activity. The methanol and aqueous extracts were found to be most effective against most of the tested organisms. The present findings significantly conform the uses of Walsura trifoliata in the indigenous systems of medicine to treat various diseases like skin allergies, astringency and diarrhoea.

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