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Journal of Medical Sciences
Year: 2012  |  Volume: 12  |  Issue: 8  |  Page No.: 280 - 285

The Quantitative Phytochemistry and Hypoglycaemic Properties of Crude Mesocarp Extract of Hyphaene thebaica (doumpalm) on Normoglycemic Wistar Albino Rats

Mohammed Shaibu Auwal, Abdulnasir Tijjani, Fatima Abba Lawan, Ismail Alhaji Mairiga, Amina Ibrahim, Abdulhamid Baba Njobdi, Abdullahi Shuaibu, Kyari Abba Sanda, Abubakar Muhammad Wakil and Ahmad Bello Thaluvwa    

Abstract: The quantitative Phytochemistry and hypoglycaemic properties of crude mesocarp extract of Hyphaene thebaica (doumpalm) on normoglycemic wistar albino rats were investigated. Fresh mesocarp of Hyphaene thebaica was bought in September 2012 from Gamboru market, Borno State, North eastern, Nigeria. One hundred and 50 g of aqueous product were prepared by reflux method from three hundred and 50 g of initial powdered sample. Phytochemical screening for biochemical and elemental contents were conducted. The quantitative phytochemical screening revealed the presence of low level of tannins, steroids and moderate level of saponins, carbohydrates, cardiac glycosides, flavonoids, terpenes and terpinoids. Elemental analysis of the extract revealed the presence of calcium, magnesium, potassium, iron and sodium in moderate concentration, manganese, zinc and silicon is low, whereas the amount of nickel, cobalt, molybdenum, arsenic and lead are negligible. Administration of crude mesocarp extract of Hyphaene thebaica in normoglycemic rats at the dosage of 400, 600 and 800 mg kg-1 for four weeks significantly (p<0.05) reduced blood glucose level of the rats at 3-4 weeks post administration. This finding validates the traditional application of Hyphaene thebaica crude mesocarp extract in the management of Diabetes mellitus in Borno State, Nigeria.

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