Asian Science Citation Index is committed to provide an authoritative, trusted and significant information by the coverage of the most important and influential journals to meet the needs of the global scientific community.  
ASCI Database
308-Lasani Town,
Sargodha Road,
Faisalabad, Pakistan
Fax: +92-41-8815544
Contact Via Web
Suggest a Journal
Journal of Medical Sciences
Year: 2012  |  Volume: 12  |  Issue: 7  |  Page No.: 214 - 218

Immunomodulatory Potential of Asparagus racemosus Wild and Chlorophytum arundinaceum Baker in Wistar rats

Manorma Sharma, Archana Sharma and Ashwani Kumar    

Abstract: The aim of present study was to evaluate immunomodulatory potential of ethanolic extract of Asparagus racemosus Wild. and Chlorophytum arundinaceum Baker. in comparison to established immunosuppressant Cedrus deodara wood oil (100 mg kg-1 b.wt.) in mice. The assessment of immunomodulatory activity on specific and nonspecific immunity was studied by Delayed Type Hypersensitivity (DTH) and neutrophil adhesion test respectively. Through Neutrophil adhesion test maximum sensitivity was observed in in vivo extract of C. arundinaceum while percent inhibition was maximum in in vitro extract of A. racemosus. In vivo Chlorophytum arundinaceum extract at 300 mg kg-1 dose statistically significantly inhibit the adhesion of neutrophils to nylon fiber. However, in vivo A. racemosus at the dose of 300 mg kg-1 was found to significantly decreased rat paw edema as compared to control, in vivo C. arundinaceumand in vitro A. racemosus extract. The present study has shown the immunomodulatory activity of both plants by potentiating humoral as well as cellular immunity.

Cited References   |    Fulltext    |   Related Articles   |   Back
  Related Articles

Copyright   |   Desclaimer   |    Privacy Policy   |   Browsers   |   Accessibility