Omega-3 Induced Change in Clinical Parameters of Rheumatoid Arthritis
The aim of this study was showing the suppressive effect of fish oil supplementation on clinical symptom in rheumatoid arthritis. Forty two patients with Rheumatoid Arthritis (RA) entered a trial to determine the clinical and biochemical effects of dietary supplementation with fractionated fish oil fatty acids. A randomized study design with 4 and 8 week treatment periods were used. Treatment with non-steroidal anti-inflammatory drugs and with disease modifying drugs was continued throughout the study. There were significant improvement of RF (p = 0.009), ESR (p = 0.003) and serum CRP (p = 0.002) after 8 weeks fish oil supplement, but after 4 weeks the RF (p = 0.004) only showed significant improvement. This study shows that dietary fish oil supplementation is effective in suppressing clinical symptoms of rheumatoid arthritis.
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