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Journal of Medical Sciences
Year: 2009  |  Volume: 9  |  Issue: 2  |  Page No.: 93 - 97

Omega-3 Induced Change in Clinical Parameters of Rheumatoid Arthritis

S.A. Hosseini, F. Rahim and K. Mola    

Abstract: The aim of this study was showing the suppressive effect of fish oil supplementation on clinical symptom in rheumatoid arthritis. Forty two patients with Rheumatoid Arthritis (RA) entered a trial to determine the clinical and biochemical effects of dietary supplementation with fractionated fish oil fatty acids. A randomized study design with 4 and 8 week treatment periods were used. Treatment with non-steroidal anti-inflammatory drugs and with disease modifying drugs was continued throughout the study. There were significant improvement of RF (p = 0.009), ESR (p = 0.003) and serum CRP (p = 0.002) after 8 weeks fish oil supplement, but after 4 weeks the RF (p = 0.004) only showed significant improvement. This study shows that dietary fish oil supplementation is effective in suppressing clinical symptoms of rheumatoid arthritis.

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