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Journal of Medical Sciences
Year: 2008  |  Volume: 8  |  Issue: 1  |  Page No.: 49 - 53

Total Antioxidant Status is Related to the CD4+ Cell Count and the Clinical State of HIV/AIDS Patients in the Northeast, Nigeria

A.C.U. Ezimah, E.A. Nwankwo, G.R.A. Okogun, J.C. Ihongbe, P.A. Onyeyili, A.C. Ene, P.U. Bassi and S.J. Yahaya    

Abstract: In this case control study, we compared the Total Antioxidant Status (TAS) of two groups of HIV positive persons that consisted of 262 AIDS patients and 158 asymptomatic HIV-antibody positive subjects with a control group of 204 HIV-antibody negative subjects. The mean CD4+ cell counts per cubic millimeter were 187 for the AIDS patients, 495 for the asymptomatic HIV patients and 920 for the control group. TAS levels in mmol L-1 were 0.34 ± 0.08 for AIDS patients, 0.77 ± 0.29 for asymptomatic patients and 1.4 ± 0.13 for controls. The CD4+ counts and TAS showed no gender biases but they differed significantly between the groups; p<0.05. The TAS was progressively depleted in HIV infected persons as the disease progressed from asymptomatic state to AIDS.

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