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Journal of Medical Sciences
Year: 2007  |  Volume: 7  |  Issue: 6  |  Page No.: 997 - 1002

Prevalence of Hepatitis C and Related Factors among Beta-Thalassemia Major Patients in Southern Iran in 2005-2006

H. Ansari, H. Kamani and A. Arbabi Sarjo    

Abstract: The purpose of this study was to assess of hepatitis C and related factors among beta-thalassemia patients. In 2005-5006 a cross sectional study was conducted in Dastgheib hospital, Shiraz, Iran. Participants were all beta-thalassemia major patients (806 cases). Blood samples were taken from patients and HCVAb was determined using commercial Kit. The data collected using a questionnaire consists on demographic and treatment related variables. Data were analyzed using chi-square test. The subjects were 400 (49.6%) females and 406 (50.4%) males. Thirty-two patients (3.9%) were more than 30 years old and 372 (46.1%) were less than 15 years old. Prevalence of this infection among males and females was 12.8 and 16%, respectively. No significant difference was seen between males and females regarding prevalence of hepatitis C (p = 0.15). The prevalence of hepatitis C was statistically correlated with type of transfused blood and blood group of patients (p = 0.05). The findings showed that despite blood screening to prevent hepatitis C, prevalence of this infection was higher among Beta-thalassemia major patients. Thus, careful screening and healthy blood transfusion is too important. It must be mentioned that packed red blood cell should be inspected with great attention and probably O blood group predispose the patients to HCV infection.

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