Plasma Zinc and Magnesium Levels in Type 2 Diabetic Patients in Gorgan City (South East of Caspian Sea-Iran)
In this study the plasma level of zinc and Magnesium were determined in 50 type 2 diabetic patients and 50 healthy people. The sampling of type 2 diabetic patients were randomized. Diabetic patients studied were without any complications. Samples were analyzed using Randox kit with Spectrophotometric method. The plasma zinc (116.78±5.51 μg dL-1) and Magnesium (1.55±0.12 meq L-1) levels significantly decreased in type 2 diabetic patients (p<0.001) when compared with control groups (146.86±9.06 μg dL-1, 1.84±0.10 meq L-1, respectively). It is concluded that type 2 diabetes mellitus can result in changes in Zinc and Magnesium levels. The decreased plasma Zn and Mg that we demonstrated in this study in patients with type 2 diabetes mellitus probably reduce insulin sensitivity and may increase risk of secondary complications, it maybe prudent in clinical practice to periodically monitor plasma Zn and Mg concentrations in type 2 diabetic patients. If plasma Zn and Mg were decreased, an intervention to increase of dietary intake of Zn and Mg may be beneficial for these patients.
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