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Journal of Medical Sciences
Year: 2002  |  Volume: 2  |  Issue: 5  |  Page No.: 237 - 239

Susceptibility of Crude Metabolites and Two Isolated Compounds of Soil Streptomyces Species to Pathogenic Organisms

Bytul M. Rahman, M.S.A. Bhuiyan, M.A.A. Al-Bari and A.S.M. Anisuzzaman    

Abstract: This investigation was an attempt to determine the primary selection of the compounds as therapeutic agents, isolated from an antagonistic Streptomyces species. The antimicrobial metabolites were extracted by CHCl3 from the fermentation broth of organism. The antimicrobial activity profile of the crude metabolites (M) as well as two isolated compounds (BM-3 and BM-5) from the crude metabolites, was interesting against some pathogenic bacteria. The minimum inhibitory concentration (MIC) of the crude metabolite (M) and compounds against six pathogenic bacteria was found to be between 16 and 64 Fg ml-1 respectively.

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