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Journal of Medical Sciences

Year: 2002  |  Volume: 2  |  Issue: 3  |  Page No.: 134 - 136

In vitro Antibacterial Activity of the Extracts and a Glycoside from Sida rhombifolia Linn

Md. Ekramul Islam, Naznin Ara Khatune and Md. Ekramul Haque


The research work was conducted to investigate the in vitro anti-bacterial activity of a glycoside, phenyl ethyl β-D-glucopyranoside, isolated from the stem of the plant Sida rhombifolia. The petroleum ether (C2H5-O-C2H5), chloroform (CHCl3) and ethylacetate (CH3-CO-O-C2H5) extracts of the plant were screened against eleven pathogenic bacteria for their antimicrobial activities. The test materials were found to be significant in vitro antibacterial activities, against most of the test bacteria. The zones of inhibition produced by the test materials were found to be between 8 and 24 mm. The minimum inhibitory concentration (MIC) values of the isolated compound was also determined against Bacillus subtilis, Sarcinia lutea, Escherichia coli and Shigella shiga which were 128, 64, 64 and 128 µg ml-1, respectively.

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