Asian Science Citation Index is committed to provide an authoritative, trusted and significant information by the coverage of the most important and influential journals to meet the needs of the global scientific community.  
ASCI Database
308-Lasani Town,
Sargodha Road,
Faisalabad, Pakistan
Fax: +92-41-8815544
Contact Via Web
Suggest a Journal
Research Journal of Microbiology
Year: 2008  |  Volume: 3  |  Issue: 4  |  Page No.: 262 - 268

Comparative Antimicrobial Activity of Commercial Disinfectants with Naphtholics

G.I. Olasehinde, J.A. Akinyanju and A.A. Ajayi    

Abstract: Studies were carried out to determine the disinfectant property of naphthol and its derivatives. The sensitivity of some clinical organisms as compared with the activity of some selected commercial disinfectants was tested. The methods employed for assessing the efficacy of disinfectants in this study are Minimal Inhibitory Concentration (MIC) Test and Capacity Use Dilution Test. The clinical organisms used for the tests are Pseudomonas aeruginosa, Salmonella typhi and Proteus mirabilis while the commercial disinfectants used are Dettol (Chloroxylenol), Savlon (Cetrimide/chlorhexidine mixture) and TCP (Trichlorophenol) and the Naphtholics are alpha naphthol and 2-amino-1,4-naphthoquinonimine hydrochloride. Dettol showed highest antibacterial activity against all the test organisms. Savlon`s antibacterial activity was high against the test organisms except Pseudomonas aeruginosa. TCP showed low activity against all the test organisms while Purified ∞-naphthol and its derivative, 2-amino-1, 4-naphthoquinonimine hydrochloride were found to exhibit disinfecting properties, with the derivative showing more antimicrobial activity than ∞-naphthol. The compounds have bactericidal effect against the test organisms used in this study.

Cited References   |    Fulltext    |   Related Articles   |   Back
 
 
   
 
 
 
  Related Articles

 
 
 
 
 
 
 
 
 
Copyright   |   Desclaimer   |    Privacy Policy   |   Browsers   |   Accessibility