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Research Journal of Microbiology
Year: 2007  |  Volume: 2  |  Issue: 1  |  Page No.: 98 - 100

Antibacterial Activity of the Marine Diatom, Rhizosolenia alata (Brightwell, 1858) Against Human Pathogens

R. Venkatesan, R. Karthikayen, R. Periyanayagi, V. Sasikala and T. Balasubramanian    

Abstract: Cultured marine diatom, Rhizosolenia alata (Brightwell) were freeze dried and extracted with solvents such as acetone, chloroform, chloroform: methanol (1:1), methanol: distilled water (4:1) and distilled water. The extracts were screened against 7 human pathogenic bacteria for their antibacterial activity. All the organic solvents showed activity against all the pathogens tested with a maximum activity in chloroform against Proteus vulgaris and minimum in chloroform: methanol against Staphylococcus aureus. However, there was no activity in distilled water extracts against all the pathogens tested.

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