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Research Journal of Microbiology

Year: 2007  |  Volume: 2  |  Issue: 11  |  Page No.: 876 - 880

Antisalmonellal Activity and Phytochemical Screening of the Various Parts of Cassia petersiana Bolle (Caesalpiniaceae)

Donatien Gatsing and Godwin I. Adoga

Abstract

Aqueous extracts of the various parts (i.e., flowers, leaves, barks and roots) of Cassia petersiana (Caesalpiniaceae) were tested for antibacterial activity against Salmonella typhi, Salmonella paratyphi A and Salmonella paratyphi B using both agar diffusion and broth dilution techniques. Phytochemical screening was also performed using standard methods. All the parts tested (at 30 mg mL-1) showed antibacterial activity against all the three bacteria strains, with the diameters of zones of inhibition ranging form 7 to 19 mm. The leaves showed the highest activity, followed by the flowers, the roots and then the barks. The MIC (Minimum Inhibitory Concentration) and MBC (Minimum Bacterial Concentration) values of the leaf extract (i.e., the most potent extract) were 1.0 and 8.0 mg mL-1, respectively, against all the three bacterial strains. Phytochemical screening gave evidence of the presence of compounds of biological interest (i.e., alkaloids, flavonoids, cardiac glycosides, antraquinones, anthocyanins, polyphenols, triterpenes, steroids, saponins, tannins and phlobatannins) in the various part of Cassia pertersiana. Anthraquinones and phlobatannins were present only in the leaf extract. These results suggest that the leaf extract may be much more recommended to the users of C. petersiana parts in the treatment of typhoid and paratyphoid fevers.

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