Histopathological Study: The Effect of Ascorbic Acid on Cadmium Exposure in Fish (Puntius altus)
The effects of cadmium and ascorbic acid on the red-tailed tinfoil barb (Puntius altus) were compared using light microscopic study for the period 24, 48, 72 and 96 h. In the gills, edema, lamellar cell hyperplasia, epithelial lifting and aneurysm were observed. In the liver, there were blood congestion in sinusoids, vacuolation of hepatocytes, hemosiderin accumulation, apoptosis and nuclear pyknosis. In the kidney, glomerulus atrophy and apoptotic cells were seen. In tubular cells, there were hydropic swelling, hyaline casts, apotosis and necrosis. Their changes occurred predominantly in the 48 h treatment. In the combination of Cd and ascorbic acid treated group, they showed similar alterations as those observed in the Cd treated alone group but they were less severe. The findings of this study can be used as guidelines for developing programs to help the fish, which are cultured near the cadmium contaminated areas.
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