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Journal of Engineering and Applied Sciences
Year: 2016  |  Volume: 11  |  Issue: 10  |  Page No.: 2136 - 2140

Evaluation of Scylla serrata Protein Extract on Hematological Parameters in Male Wistar Rats

Nur Syahiirah Saberi, Mazura Bahari, Mohd Nazri Abu, Mohd Fahmi Mastuki, Wan Shahriman Yushdie Wan Yusoff and Evana Kamarudin    

Abstract: This study aimed to determine the potential of the Mud crab (Scylla serrata) as a source to treat blood disorders. Eighteen male Wistar rats were randomly divided into three groups (2 treatment groups and 1 control group) of six rats (n = 6). All groups were kept under similar condition. Mud crab stock solutions were prepared in 7.0 mg mL–1 protein/kg and 52 mg mL–1 protein/kg doses and orally administered to treatment groups for three weeks. Distilled water was used for the control group. Blood samples were obtained from each rat via cardiac puncture for further analysis of various haematological parameters. The result revealed that the average protein content of the extract was 5.2±0.06 mg mL–1 protein/kg. RBC, Hb, HCT and MCH level increased significantly in the treatment groups compared to control group. In conclusion, mud crab contains vital nutrients that boost production of red blood cell indices, hence could serve as an essential food supplement to treat anemia.

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