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Journal of Clinical Microbiology
Year: 2008  |  Volume: 46  |  Issue: 12  |  Page No.: 4075 - 4077

Characterization of Extensively Drug-Resistant Mycobacterium tuberculosis Clinical Isolates in China

Zhaogang Sun, Yanjie Chao, Xuxia Zhang, Jianyuan Zhang, Yan Li, Yunqing Qiu, Yi Liu, Lihui Nie, Aizhen Guo and Chuanyou Li    

Abstract: Thirteen extensively drug-resistant tuberculosis isolates which were highly resistant to a broad spectrum of antituberculosis drugs were identified from 1,926 clinical isolates in China. They had highly diverse mycobacterial interspersed repetitive-unit-variable-number tandem-repeat patterns. Most, but not all, of the drug target genes had mutations contributing to resistance to the corresponding drug.

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