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Journal of Clinical Lipidology
Year: 2012  |  Volume: 6  |  Issue: 3  |  Page No.: 272 - 273

Statin Therapy Alters the Relationship Between Apolipoprotein B and Both LDL-C and Non-HDL-C in High-Risk Patients: Effect of Race/Ethnic Background

Christie M. Ballantyne, Stephen J. Nicholls, Philip J. Barter, Valerie A. Cain and Joel S. Raichlen    

Abstract: Racial and ethnic subgroups are frequently underrepresented in clinical trials of statin therapy. Apolipoprotein (Apo) B provides a measure of atherogenic particles in blood, a predictor for coronary heart disease (CHD) events. Reducing low-density lipoprotein cholesterol (LDL-C) to current goals may still leave an excess of atherogenic lipoproteins. A study of predominantly white high-risk patients suggested that statin therapy may alter the relationship between Apo B and commonly measured lipoproteins.

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