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Year: 2010 | Volume: 188 | Issue: 4 | Page No.: 547 - 563
M Koivusalo, C Welch, H Hayashi, C. C Scott, M Kim, T Alexander, N Touret, K. M Hahn and S. Grinstein
Abstract
Inhibitors of Na+/H+ exchange proteins block macropinocytosis by lowering the pH near the plasma membrane, which in turn inhibits actin remodeling by Rho family GTPases.