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The Journal of Cell Biology
Year: 2010  |  Volume: 189  |  Issue: 1  |  Page No.: 127 - 141

Cross talk between microRNA and epigenetic regulation in adult neurogenesis

K. E Szulwach, X Li, R. D Smrt, Y Li, Y Luo, L Lin, N. J Santistevan, W Li, X Zhao and P. Jin    

Abstract:

The microRNA miR-137 represses expression of Ezh2, a histone methyltransferase, which in turn alters the epigenetic architecture of chromatin that is important for regulation of miR-137 levels.

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