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The Journal of Cell Biology

Year: 2009  |  Volume: 186  |  Issue: 6  |  Page No.: 805 - 816

The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice

J Wakabayashi, Z Zhang, N Wakabayashi, Y Tamura, M Fukaya, T. W Kensler, M Iijima and H. Sesaki

Abstract

Brain-specific Drp1 knockout mice demonstrate that Drp1-mediated organelle division is important for development, mitochondrial morphogenesis, and apoptosis.

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