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Journal of Biological Sciences
Year: 2008  |  Volume: 8  |  Issue: 4  |  Page No.: 831 - 833

Anthelminthic Activity of Cansjera rheedii J. Gmelin (Opiliaceae)

V.M. Mounnissamy, S. Kavimani, V. Balu and S. Darlin Quine    

Abstract: The ethanol, water and chloroform extracts of the aerial parts of Cansjera rheedii J. Gmelin (Opiliaceae) were investigated for activity against Indian earthworms Pheretima posthuma. Various concentrations (5-40 mg mL-1) of each extract were tested, which involved determination of time of paralysis and time of death of the worms. All three extracts exhibited considerable anthelminthic activity. All the extracts (i.e., aqueous, chloroform and ethanol) at the tested dose (5-40 mg mL-1) level produced significant activity (p < 0.001) when compared with piperazine citrate (15 mg mL-1) and albendazole (20 mg mL-1) which were included as standard reference and normal saline as control. The present study indicates the potential usefulness of Cansjera rheedii aerial parts as anthelminthic activity.

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