Asian Science Citation Index is committed to provide an authoritative, trusted and significant information by the coverage of the most important and influential journals to meet the needs of the global scientific community.  
ASCI Database
308-Lasani Town,
Sargodha Road,
Faisalabad, Pakistan
Fax: +92-41-8815544
Contact Via Web
Suggest a Journal
Journal of Biological Sciences
Year: 2008  |  Volume: 8  |  Issue: 4  |  Page No.: 738 - 745

Ultrastructural Alterations in Testis and Gastrodermis of Schistosoma mansoni Due to Treatment of Infected Mice with the New Rhodanine Derivative Ro-354

Mohammad I. Soliman    

Abstract: Ultrastructural changes in Schistosoma mansoni isolated from mice up to 2 weeks after dosing with 50 mg kg1 body weight Ro-354 were investigated. The testicular follicles were completely disorganized. Signs of degeneration of non-germinal cells, vacuolization and swelling of spermatogonia, degeneration of spermatocytes and regression of spermatids were also observed. All stages of spermiogenesis were regressed and developing spermatozoa showed abnormal morphology. As to gastrodermis, a dramatic decrease in the number of surface amplifications (microvilli) was observed. Blebbing, formation of lipid granules, degeneration and prominent flattening of the gastrodermis followed by a general erosion of the tissue to the basal lamina.

Cited References   |    Fulltext    |   Related Articles   |   Back
   
 
 
 
  Related Articles

 
 
 
 
Copyright   |   Desclaimer   |    Privacy Policy   |   Browsers   |   Accessibility