Effect of Vitamin C Supplementation on Oxidative Stress Markers Following Thirty Minutes Moderate Intensity Exercise in Healthy Young Women
The aim of this double blind randomized controlled trial
was to determine the effect of Vitamin C supplementation on oxidative
stress following 30 min moderate intensity exercise. Forty-nine healthy
young women randomly assigned into 500 mg day-1 vitamin C supplement
(n = 25) or placebo (n = 24) groups for two weeks. Before supplementation
and on the day after the intervention period, fasting blood samples were
taken. Then all participants ran (1.4-1.7 m sec-1) for 30 min.
Third blood samples were taken at the end of exercise. Plasma malondialdehyde
(MDA) and vitamin C were measured using HPLC method. Plasma total glutathione
was measured with ELISA method. No significant differences were observed
in demographic and vitamin C intakes before intervention between groups.
Plasma MDA levels decreased and plasma total glutathione increased significantly
(p<0.05) in both groups. No significant differences were observed between
groups after exercise. There were significant differences in plasma vitamin
C concentrations after intervention and exercise between groups. In conclusion,
vitamin C supplementation (500 mg day-1) for two weeks does
not affect oxidative stress markers following moderate intensity exercise
in healthy young women.
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