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Journal of Biological Sciences
Year: 2007  |  Volume: 7  |  Issue: 5  |  Page No.: 815 - 818

Effects of Aqueous Extract of Anethum graveolens (L.) On Male Reproductive System of Rats

Monsefi Malihezaman and Pahlavan Sara    

Abstract: Involvement of men in control of population is lesser than women that may be due the limited contraceptive choices. For this purpose, the infertility effect of plants such as Anethum graveolens (L.) that used in folk remedy to decrease male fertility have been tested in animal models. Thirty adult male Wistar rats were divided into 3 groups of treatment group I, 70 mg kg-1, treatment group II, 100 mg kg-1 of aqueous extract that received in a volume of 1 mL by gavage daily for 32 days and control group were treated with 1 mL of distilled water. Body weights of all animals were recorded before and after of experiment. Serum testosterone levels at the beginning and the end of the experiment were measured. The animals were sacrificed and left testis, epididymis, seminal vesicle and prostate were dissected out and weighted. Sperm count, motility and nuclear maturity were examined. After tissue preparation of testis, seminiferous tubular diameter were measured and frequency of stages. After tissue preparation of testis, seminiferous tubular diameter were measured and frequency of stage of the the germinal epithelium cycle of seminiferous tubules were evaluated by using staging map. The treatment did not affect body and organ weight, serum testosterone levels, sperm count, motility and nuclear maturity from that of the control group. Spermatogenic cycle in seminiferous tubules and seminiferous tubular diameter did not altered by the treatment. These results suggest anti fertility effect for Anethum graveolens seed aqueous extract in rats at levels of 70 and 100 mg kg-1.

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