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Journal of Biological Sciences
Year: 2007  |  Volume: 7  |  Issue: 2  |  Page No.: 255 - 262

Hydroalcoholic Extract of Terminalia arjuna:A Potential Hepatoprotective Herb

U. Subasini, G.V. Rajamanickam, G.P. Dubey, P.C. Prabu, C. Savariraj Sahayam, M. Mohammed Shabi, K. Gayathri and Aruna Agrawal    

Abstract: Herbal drugs are considered to be the best alternative for many diseases. Even incurable diseases like cancer, HIV, etc., are moving towards the traditional herbal drugs. The treatment using herbal drugs is gaining momentum to the vital organs like liver, kidney and heart. In such movement, the finding of the presence of effectiveness of hepatoprotective factor from any plant is felt a contributory one. Terminalia arjuna a plant commonly observed in the south India is found to have a property of hepatoprotectiveness. In order to appreciate the hepatoprotective activity of the Terminalia arjuna, hydroalcoholic extract of the same is used here on Albino Wistar mice. The general behaviour of the animals has been studied in comparison to control group with the Terminalia arjuna extract treated animals. A gross pathology and histopathology have also been studied. The results obtained from the study of GOT, GPT and ALP clearly direct the hepatoprotective effectiveness of hydroalcoholic extract of Terminalia arjuna.

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