Asian Science Citation Index is committed to provide an authoritative, trusted and significant information by the coverage of the most important and influential journals to meet the needs of the global scientific community.  
ASCI Database
308-Lasani Town,
Sargodha Road,
Faisalabad, Pakistan
Fax: +92-41-8815544
Contact Via Web
Suggest a Journal
Journal of Biological Sciences
Year: 2007  |  Volume: 7  |  Issue: 7  |  Page No.: 1233 - 1238

In vitro Antibacterial Potentials of the Stem Bark of Red Water Tree (Erythrophleum suaveolens)

O.A. Aiyegoro, D.A. Akinpelu and A.I. Okoh    

Abstract: The antibacterial potentials of Erythrophleum suaveolens against some selected bacterial isolates were investigated. The aqueous and chloroform fractions of the plant extract exhibited significant inhibitory action against eight of the twelve bacterial isolates tested at a concentration of 10 mg mL-1. The zones of inhibition exhibited by the extract ranged between 8 and 15 mm. The Minimum Inhibitory Concentration (MIC) of the aqueous fraction of extract ranged between 0.625 and 2.5 mg mL-1, while that of chloroform fraction ranged between 0.313 and 5.0 mg mL-1. Also, between 40 and 80% of the test organisms were killed over a period of 2 h in extract concentrations of between 0.078 and 0.625 mg mL-1. Phytochemical analysis of the Erythrophleum suaveolens extract revealed the presence of saponins, tannins, steroids and alkaloid. Overall, the two fractions compared favorably with the standard antibiotics, streptomycin and ampicillin at concentration of 1 mg mL-1 and 10 μg mL-1, respectively. Cell disruption is proposed as the mechanism of action of the aqueous fraction of the plant extract.

Cited References   |    Fulltext    |   Related Articles   |   Back
   
 
 
 
  Related Articles

 
 
 
 
 
 
 
 
 
Copyright   |   Desclaimer   |    Privacy Policy   |   Browsers   |   Accessibility