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Journal of Biological Sciences
Year: 2004  |  Volume: 4  |  Issue: 4  |  Page No.: 527 - 531

In vitro Studies of Antimicrobial Activity of Synthetic Ovaliflavone

Sayed Alam, M.A. Jalil Miah and Azizul Islam    

Abstract: In the present study 8-γ,γ-dimethyallyl-5, 7-dimethoxyflavone [ovaliflavone, 6] has been synthesized from phloroacetophenone via chalcone precursor and by its treatment with DMSO/I2 or diphenyl sulphide. The antibacterial and antifungal activities of ovaliflavone and its corresponding chalcone were found in vitro by the filter paper disc diffusion method and poisoned food technique, respectively. Compound 6 showed good antibacterial and antifungal activities to the some selected bacterial and fungal strain.

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