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Journal of Biological Sciences
Year: 2003  |  Volume: 3  |  Issue: 12  |  Page No.: 1140 - 1147

Combined Sedation and Regional Analgesia in Black Bengal Goats of Bangladesh

S.J. Sherajee, K. Rafiq, N.S. Juyena, S. Ahmed and M.A. Hashim    

Abstract: To find out the effect of diazepam and promethazine hydrochloride on respiratory rate, pulse rate, temperature and production of clinical signs in goats and also to compare the effect of 2% lignocaine hydrochloride and 0.5% bupivacaine hydrochloride during paravertebral and epidural analgesia were investigated. A total of 16 apparently healthy Black Bengal goats with body weight of 8-12 (median 9.5 kg) kg were used and allocated in 8 groups. Both diazepam and promethazine, were used as sedatives. Diazepam and promethazine produced significant reduction (P<0.01) of respiratory rate and significantly (P<0.01) increase of the pulse rate, respectively. But both drugs produced reduction of temperature insignificantly. The important clinical signs recorded using diazepam was movement of legs, neck, salivation and sleepiness whereas with promethazine only a tranquilizing effect was recorded. With 2% lignocaine hydrochloride the onset of analgesia was rapid compared to 0.5 bupivacaine hydrochloride. But the duration was significantly longer in 0.5% bupivacaine than that of 2% lignocaine hydrochloride. Muscle relaxation was better with 2% lignocaine hydrochloride compared to 0.5% bupivacaine hydrochloride. This experiment suggested that both diazepam and promethazine are suitable as pre-medicants in goats and bupivacaine seemed to be better for longer duration of analgesia compared to lignocaine which may be used for shorter and minor surgery in goats.

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