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Journal of Biological Sciences
Year: 2001  |  Volume: 1  |  Issue: 6  |  Page No.: 505 - 506

The Role of Hydroximate Type Siderophore on Cr+3 Concentration in Biological System

M. Zulqurnain, M. Tariq and Fouzia. S .Rehmani    

Abstract: In iron overload condition a drug desferioxamine mesylate has been used. It is linear trihydroxamic acid, a natural siderophore produced nocardia and streptomyces. The complex formation of Cr+3 and Fe+3 with salicylhydroxamic were studied potentiometrically at different temperatures. The data were subjected to computer program "BEST". The stability constant values and thermodynamic stabilities were calculated. It was found that salicylhydroxamate forms 1:1 complex at pH 3 and 1: 2 complex at pH 4 with Cr+3. The stability constant and thermodynamic abilities are close to Fe+3 salicyl hydroxamate complexes.

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