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Journal of Animal and Veterinary Advances
Year: 2014  |  Volume: 13  |  Issue: 20  |  Page No.: 1160 - 1166

The Potential Effect of Camel Milk and Urine Against CCL4-Induced Lesions in Male Rats

Salah Abdulaziz Al-Shami, Nagwan El-Habashi, Mohamed A. Mandour, Yehia Ahmed Hussein and Marzook Mohamed Al-Eknah    

Abstract: This study was designed to explore the potential of camel milk and urine and their protective effects against Carbon Tetrachloride (CCL4) intoxication in male rats. Six experimental groups of two dietary regimes (milk, urine and their mixture) before and after CCL4 injection were evaluated in comparison with positive (CCL4 only) and negative control groups. Camel urine and milk were diluted by water (1:3 and 1:1 v/v). The diluted urine and milk were mixed in equal volumes directly before fed to rats. The results revealed the occurrence of the highest histopathological changes in testis, liver and kidney of the CCL4 treated group. Feeding urine or milk prior CCL4 intoxication showed almost complete to moderate retrieval of the induced lesions. Milk urine mixture showed retrieval of the induced lesions in testis, however; gave lesions similar degree to those seen in liver and kidneys. CCL4 injection then feeding trial revealed that urine and milk reduced the induced lesions by the same degree in testis and liver. This study point to the possible protective potential of camel milk and urine (in prophylaxis or treatment) against the CCL4-induced damage.

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