Asian Science Citation Index is committed to provide an authoritative, trusted and significant information by the coverage of the most important and influential journals to meet the needs of the global scientific community.  
ASCI Database
308-Lasani Town,
Sargodha Road,
Faisalabad, Pakistan
Fax: +92-41-8815544
Contact Via Web
Suggest a Journal
Journal of Animal and Veterinary Advances
Year: 2012  |  Volume: 11  |  Issue: 10  |  Page No.: 1574 - 1577

Sodium Salicylate Attenuates Acute Stress Responses to Castration in Calves

Ken Onda, Yukiko Emura, Aya Saito, Tooru Ikeyama, Reiichiro Sato, Hideharu Ochiai, Kazuyuki Kaneko, Tsunenori Iriki and Yasunori Wada    

Abstract: Acute stress following surgical castration of calves is a common animal welfare concern. Administration of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) can reduce post-castration stress but treatments vary in cost and efficacy. In this study, the effectiveness of sodium salicylate in relieving stress during invasive castration of calves was assessed on the basis of changes in serum cortisol levels and was compared with the effectiveness of ketoprofen. Twenty male Holstein calves were divided into 4 groups: a sham-operated untreated group, a castrated untreated group and 2 castrated groups receiving NSAIDs (sodium salicylate or ketoprofen). NSAIDs were injected intravenously immediately before administering local anesthetic. Blood samples were collected at regular time intervals for measurement of cortisol concentrations. Serum cortisol concentrations of the calves that were administered sodium salicylate were lower than those of the calves that were not administered any NSAID at 1, 1.5 and 2 h after castration and higher than those of the calves that were administered ketoprofen at 2 h after castration (p<0.05). Although, the analgesic and anti-inflammatory effects of sodium salicylate are weaker than those of ketoprofen, the use of salicylic acid derivatives in surgical castration is useful from the viewpoint of animal welfare and entails a significantly lower cost.

Fulltext    |   Related Articles   |   Back
  Related Articles

Copyright   |   Desclaimer   |    Privacy Policy   |   Browsers   |   Accessibility