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Journal of Applied Sciences
Year: 2007  |  Volume: 7  |  Issue: 20  |  Page No.: 3127 - 3130

Xanthine Oxidase Inhibitor Activity of Terpenoid and Pyrrole Compounds Isolated from Snake Fruit (Salacca edulis Reinw.) cv. Bongkok

Leni Herliani Afrianti Priyatno, Elin Yulinah Sukandar, Slamet Ibrahim and I. Ketut Adnyana    

Abstract: The compound of 3β-hydroxy-sitosterol (1) and 2-metylester-1-H-pyrrole-4-carboxilyc acid were isolated from ethyl acetate extract of snake fruit (Salacca edulis Reinw) cv. Bongkok, (2). Inhibition of xanthine oxidase by the two compounds were evaluated against enzyme of xanthine oxidase. Compound 1 could be regarded as inactive, while compound 2 was found to be active with IC50 value of 48.86 μg mL-1.

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