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Journal of Applied Sciences
Year: 2006  |  Volume: 6  |  Issue: 10  |  Page No.: 2251 - 2256

Free Radical Scavenging Activity of Mussaenda glabra

K.S. Vidyalakshmi, A.I. Charles Dorni, Hannah R. Vasanthi, G.V. Rajamanickam and D. Sukumar    

Abstract: The flowers of Mussaenda glabra occurring in white and pink have been evaluated for their anti oxidant property. The white (MGW) and the pink (MGP) varieties showed considerable NO scavenging activity. The IC50 values were found to be 92.79 and 122.45 μg mL-1, respectively. MGW inhibited lipid peroxidation to a greater extent when compared to MGP. MGW showed 50% inhibition at the concentration of 112.4 μg mL-1 while MGP at 53.42 μg mL-1. The reducing power was found in a dose dependent manner. The pink variety showed greater reducing power when compared to white variety. Both the extracts showed hydroxyl radical and ABTS radical scavenging property. The total phenolic content was 17.5 and 8.3 mg g-1 in MGP and MGW, respectively. The HPTLC fingerprinting showed peaks due to flavonoids. The results show that both are having considerable anti oxidant property. The abundance of this flower throughout the year can be used for evaluating its medicinal value.

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