Asian Science Citation Index is committed to provide an authoritative, trusted and significant information by the coverage of the most important and influential journals to meet the needs of the global scientific community.  
ASCI Database
308-Lasani Town,
Sargodha Road,
Faisalabad, Pakistan
Fax: +92-41-8815544
Contact Via Web
Suggest a Journal
Journal of Applied Sciences
Year: 2006  |  Volume: 6  |  Issue: 7  |  Page No.: 1625 - 1627

Electrochemical Behavior and the Determination of Omeprazole Using Glassy Carbon Electrode

Jin-Long Yan    

Abstract: The electrochemical behavior of omeprazole on a glassy carbon electrode was investigated by cyclic voltammetry and differential pulse voltammetry. It was found that omeprazole would give a sensitive oxidation peak at +0.74 V in the HAc-NaAc buffer solution (pH 5.10) under the Differential Pulse Voltammetric (DPV) mode. The peak current was linear with the concentration of omeprazole in the range of 1.0~20 mg L-1. Based on which, a DPV method for determination of omeprazole with the detection limit of 0.19 mg L-1 has been developed. The proposed method has been used for determination of omeprazole concentration in omeprazole enteric-coated tablets, the recovery was found to be in the range of 99.3~102%. The mechanism for this electrochemical reaction at the glassy carbon electrode was also discussed in this study.

Cited References   |    Fulltext    |   Related Articles   |   Back
 
 
   
 
 
 
  Related Articles

 
 
 
 
 
 
 
 
 
Copyright   |   Desclaimer   |    Privacy Policy   |   Browsers   |   Accessibility