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International Journal of Pharmacology
Year: 2010  |  Volume: 6  |  Issue: 5  |  Page No.: 712 - 718

Effect of Matricaria chamomilla L. Plant Extraction on Experimental Infected Lamb with Ostertagia ostertagi Parasits

A.M. Bahrami, A. Doosti and A.B. Moosavi    

Abstract: This study was conducted in Ilam province Iran, to evaluate the effects of homeopathic treatment on control of Ostertagia ostertagi experimental infection in lamb and weight gain after treatment with the ethanol extraction of Matricaria chamomilla L. plant and haematological changes due to this parasitic infection. Herdsman do believed that feeding of Matricaria chamomilla L. plant in limited amounts could help to keep lamb more healthy and can act as an antihelminthic. The plasma protein (by SDS-PAGE) and enzyme levels were studied in Kordish breed lamb infected with (10000L3) O. ostertagi orally. Twenty four lambs age between 8-12 months, with the average weight 13.650 kg were divided in two groups 1 as control and the group 2 as an experimental animal infected with O. ostertagi and after 10 weeks of parasitic infection the experimental groups were de wormed with 5 mL kg-1 b.wt. Matricaria chamomilla L. plant extraction. Plasma of blood sample was separated for determination of total protein, plasma total free amino and alkaline phosphates. At the results significant decrease in plasma total free amino acid and total plasma protein and significant increase in alkaline phosphates and acid phosphates were seen in infected group. Significant increase were observed in infected lamb after 10 weeks de worming the animal with experiment plant extraction. It can be concluded that M. chamomilla can be use as a de wormer, or can say that it is effective for increasing the body weight of animals, its need further investigation.

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