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International Journal of Pharmacology
Year: 2010  |  Volume: 6  |  Issue: 1  |  Page No.: 53 - 57

In vivo Hair Growth Activity of Herbal Formulations

M. Semalty, A. Semalty, Geeta P. Joshi and M.S.M. Rawat    

Abstract: The present study deals with the assessment of hair growth potential of three plants, Semecarpus anacardium, Trigonella foenumgraecum and Trigonella corniculata. Petroleum ether and ethanolic extracts of all the plants were prepared. Aloe vera gel (prepared with fresh Aloe vera leaves) based herbal formulations were prepared with both types of extracts of each plant. The formulations were subjected to characterization of pH, texture, odour and toxicity studies. Hair growth activity of the formulations was studied in comparison of 2% minoxidil solution (standard) in albino rats for 30 days. It was concluded that T. foenumgraecum showed the best hair growth activity. Formulation containing T. foenumgraecum petroleum ether extract showed the minimum time to initiate (5 days) as well as to complete the hair growth (18 days) at denuded surfaces. Formulation with T. foenumgraecum ethanolic extract showed the best hair lengthening properties as compared to others. The study concluded that even the short-term treatment with these herbal formulations is effective in significant hair growth promotion.

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